Dietary Supplementation of Gingerols- and Shogaols-Enriched Ginger Root Extracts Attenuate Pain-Associated Behaviors in Animals with Spinal Nerve Ligation
نویسندگان
چکیده
منابع مشابه
Activation of neurotrophins in lumbar dorsal root probably contributes to neuropathic pain after spinal nerve ligation
Objective(s): Neurotrophins (NTs) exert various effects on neuronal system. Growing evidence indicates that NTs are involved in the pathophysiology of neuropathic pain. However, the exact role of these proteins in modulating nociceptive signaling requires being defined. Thus, the aim of this study was to evaluate the effects of spinal nerve ligation (SNL) on NTs activation in the lumbar dorsal ...
متن کاملAge-Related Differences in Neuropathic Pain Behavior and Spinal Microglial Activity after L5 Spinal Nerve Ligation in Male Rats
Introduction: Several studies have reported the involvement of age-related changes in the development of neuropathic pain behaviors. However, limited data are available on the role of age in establishing and maintaining chronic neuropathic pain after peripheral nerve injury. Methods: In the present study, we examined age-related neuropathic behavior among rats in 4 age groups: p...
متن کاملactivation of neurotrophins in lumbar dorsal root probably contributes to neuropathic pain after spinal nerve ligation
objective(s): neurotrophins (nts) exert various effects on neuronal system. growing evidence indicates that nts are involved in the pathophysiology of neuropathic pain. however, the exact role of these proteins in modulating nociceptive signaling requires being defined. thus, the aim of this study was to evaluate the effects of spinal nerve ligation (snl) on nts activation in the lumbar dorsal ...
متن کاملNMDA RECEPTOR ANTAGONISTS ATTENUATE TOLERANCE INDUCED BY MORPHINE AND NERVE LIGATION IN MICE
The effect of NMDA (N-methyl-D-aspartate) receptor antagonists on tolerance to morphine antinociception was investigated in mice. Daily subcutaneous administration of 50 mg/kg of morphine hydrochloride for three days induced tolerance to different (3,6 and 9 mg/kg) test doses of morphine. The tolerance obtained was decreased by pretreatment of animals with single or repeated doses of compe...
متن کاملActivation of neurotrophins in lumbar dorsal root probably contributes to neuropathic pain after spinal nerve ligation
OBJECTIVES Neurotrophins (NTs) exert various effects on neuronal system. Growing evidence indicates that NTs are involved in the pathophysiology of neuropathic pain. However, the exact role of these proteins in modulating nociceptive signaling requires being defined. Thus, the aim of this study was to evaluate the effects of spinal nerve ligation (SNL) on NTs activation in the lumbar dorsal roo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Developments in Nutrition
سال: 2020
ISSN: 2475-2991
DOI: 10.1093/cdn/nzaa040_074